mouse tumor ulceration

For some people, an ulcerating tumour is the most upsetting aspect of their cancer. } (1) KPC mice develop a spectrum of premalignant lesions called Pancreatic Intraepithelial Neoplasia (PanINs) that ultimately . .tablepress .column-1 { In the syngeneic tumor mouse model, hPD-L1 expressing CT-26 cells (0.5 x 10. Humane endpoints to euthanize mice were tumor volumes greater than 2000 mm 3, loss of > 20% body weight, and ulceration or severe necrosis of tumor. !function(e,a,t){var n,r,o,i=a.createElement("canvas"),p=i.getContext&&i.getContext("2d");function s(e,t){var a=String.fromCharCode;p.clearRect(0,0,i.width,i.height),p.fillText(a.apply(this,e),0,0);e=i.toDataURL();return p.clearRect(0,0,i.width,i.height),p.fillText(a.apply(this,t),0,0),e===i.toDataURL()}function c(e){var t=a.createElement("script");t.src=e,t.defer=t.type="text/javascript",a.getElementsByTagName("head")[0].appendChild(t)}for(o=Array("flag","emoji"),t.supports={everything:!0,everythingExceptFlag:!0},r=0;r h1 { color: #000000 } #masthead .hgroup .support-text, #masthead .hgroup .site-description { font-size: 28px; color: #000000 } #page-title, article.post .entry-header h1.entry-title, article.page .entry-header h1.entry-title { font-size: 32px; color: #000000 } .entry-content { font-size: 16px } .entry-content, #comments .commentlist article .comment-meta a { color: #000000 } .entry-content h1, .entry-content h2, .entry-content h3, .entry-content h4, .entry-content h5, .entry-content h6, #comments .commentlist article .comment-author a, #comments .commentlist article .comment-author, #comments-title, #reply-title, #commentform label { color: #000000 } #comments-title, #reply-title { border-bottom-color: #000000 } .entry-content h1 { font-size: 32px } .entry-content h2 { font-size: 28px } .entry-content h3 { font-size: 24px } .entry-content h4 { font-size: 20px } .entry-content h5 { font-size: 18px } .entry-content h6 { font-size: 16px } #masthead .hgroup { padding-top: 25px; 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